联系我们 | 在线留言 | 注册 | 忘记密码
读者在线:用户名 密码 登录
首页期刊简介编委会读者·作者园地编辑部消息投稿须知期刊订阅我的账户
电子期刊 >> 正文
结核性脑膜炎脑脊液免疫学诊断
作者:许自强        张昆南 
单位:许自强(南昌大学研究生院医学部 江西 南昌 330006)张昆南(江西省人民医院神经内科 江西 南昌330006) 
关键词:结核性脑膜炎      脑脊液      诊断 
分类号:R529.3
出版年,卷(期):页码:2009,16(6):0-0
摘要:
结核性脑膜炎(tuberculous meningitis,TBM)是一种病死率和致残率很高的中枢神经系统感染性疾病,临床表现缺乏特异性,病情变化迅速,早期诊断困难.近年来,TBM的脑脊液(CSF)免疫学诊断以其极高的敏感性和特异性得到迅速发展,临床应用前景广阔.现就TBM的CSF免疫学诊断做一综述.
基金项目:
作者简介:
参考文献:
Thwaites GE,Chau TT,Stepniewska K,et al.Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features[J].Lancet,2002,360(9342):1287-1292. Thwaites GE,Nguyen DB,Nquyen HD,et al.Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults[J].N Engl J Med,2004,351(17):1741-1751. Kulkarni SP,Jaleel MA,Kadival GV.Evaluation of an in-house-developed PCR for the diagnosis of tuberculous meningitis in Indian children[J].J Med Microbiol,2005,54(Pt4):369-373. Sumi MG,Mathai A,Reuben S,et al.Immunocytochemical method for early laboratory diagnosis of tuberculous meningitis[J].Clin Diagn Lab Immunol,2002,9(2):344-347. Kashyap RS,Kainthla RP,Biswas SK,et al.Rapid diagnosis of tuberculous meningitis using the simple Dot ELISA method[J].Med Sci Monit,2003,9(11):MT123-126. Mathai A,Radhakrishnan VV,Sarada C,et al.Detection of heat stable mycobacterial antigen in cerebrospinal fluid by Dot-Immunobinding assay[J].Neurol India,2003,51(1):52-54. Kashyap RS,Dobos KM,Belisle JT,et al.Demonstration of components of antigen 85 complex in cerebrospinal fluid of tuberculous meningitis patients[J].Clin Diagn Lab Immunol,2005,12 (6):752-758. Venkatesh K,Parija SC,Mahadevan S,et al.Reverse passive haemagglutination (RPHA) test for detection of mycobacterial antigen in the cerebrospinal fluid for diagnosis of tubercular meningitis[J].Indian J Tuberc,2007,54(1):41-48. 丁晓旭,薛承岩.脑脊液和血液标本检测阿拉伯糖甘露糖脂G抗体诊断结核性脑膜炎的价值[J].临床荟萃,2007,22 (4):284-286. 李永刚,杨昆胜,晋华文,等.脂阿拉伯甘露聚糖诊断结核性脑膜炎的评价[J].中国防痨杂志,2005,27(5):316-319. Demkow U,Filewska M,Bialas B,et al.Antimycobacterial antibody level in pleural,pericardial and cerebrospinal fluid of patients with tuberculosis[J].Pneumonol Alergol Pol,2004,72(3-4):105-110. Kashyap RS,Kainithla RP,Satpute RM,et al.Demonstration of IgG antibodies to 30 Kd protein antigen in CSF for diagnosis of tuberculous meningitis by antibody capturing ELISA[J].Neurol India,2004,52(3):359-362. 王仲元,陈红兵,何秀云,等.斑点酶免疫渗滤法抗体检测对结核性脑膜炎诊断价值的评估[J].北京医学,2005,27(2):120-121. Quan C,Lu CZ,Qiao J,et al.Comparative evaluation of early diagnosis of tuberculous meningitis by different assays[J].J Clin Microbiol,2006,44(9):3160-3166. Restrepo BI,Pino PA,Volcy M,et al.Interpretation of mycobacterial antibodies in the cerebrospinal fluid of adults with tuberculous meningitis[J].Trop Med Int Health,2008,13(5):653-658. Luca MC,Petrovici CM,Vtǎ A,et al.Gamma interferon testing in blood and cerebrospinal fluid--rapid method for the diagnosis of tuberculous meningitis[J].Rev Med Chir Soc Med Nat Iasi,2008,112(1):108-110. Thomas MM,Hinks TS,Raghuraman S,et al.Rapid diagnosis of mycobacterium tuberculosis meningitis by enumeration of cerebrospinal fluid antigen-specific T-cells[J].Int J Tuberc Lung Dis,2008,12(6):651-657. Murakami S,Takeno M,Oka H,et al.Diagnosis of tuberculous meningitis due to detection of ESAT-6-specific gamma interferon production in cerebrospinal fluid enzyme-linked immunospot assay[J].Clin Vaccine Immunol,2008,15(5):897-899.
服务与反馈:
文章下载】【加入收藏
中国神经免疫学和神经病学杂志 © 2009
编辑部地址:北京东单大华路1号   电话:010-58115071
传真:010-65242081   邮箱:zgsm@263.net