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定量PCR法对缺失型DMD家系携带者诊断价值的研究
作者:杨渝        钟月桂        江滢        彭福华        YANG Yu        ZHONG Yue-gui        JIANG Ying        PENG Fu-hua 
单位:中山大学附属第三医院神经科 广东 广州 510630 
关键词:杜(氏)/贝(氏)进行性肌营养不良      携带者      定量PCR 
分类号:R74
出版年,卷(期):页码:2007,14(6):0-0
摘要:
目的 探讨紫外凝胶分析系统定量PCR方法对缺失型杜(氏)/贝(氏)进行性肌营养不良(DMD/BMD)携带者的诊断价值. 方法采用紫外凝胶分析系统定量检测16个缺失型DMD/BMD家系中的19名女性亲属和15名健康对照的二重PCR产物,并计算计量系数DQ值.结果 定量PCR方法将9名女性确定为携带者.结论 定量PCR方法是一种准确、快速、简便的DMD携带者诊断方法.
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参考文献:
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