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磷脂酶A2在多发性硬化发病中的作用
作者:徐全刚        吴卫平 
单位:中国人民解放军总医院神经内科 北京 100853 
关键词:多发性硬化      磷脂酶 A2 
分类号:R744.5+1
出版年,卷(期):页码:2004,11(5):0-0
摘要:
多发性硬化(multiple sclerosis,MS)的发病机制目前仍不清楚,中枢神经系统(CNS)中大量炎性因子释放、炎性细胞浸润以及髓鞘脱失是其病变的基础.磷脂酶A2(phospholipase A2,PLA2)通过诱导CNS内多种趋化因子、细胞因子产生并促进CNS炎性反应、脱髓鞘及轴索损害,在MS中发挥重要致病作用.
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参考文献:
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