联系我们 | 在线留言 | 注册 | 忘记密码
读者在线:用户名 密码 登录
首页期刊简介编委会读者·作者园地编辑部消息投稿须知期刊订阅我的账户
电子期刊 >> 正文
趋化因子与免疫介导的中枢神经系统炎性反应(综述)
作者:周文斌        肖波        谢光洁 
单位:中南大学湘雅医院神经内科  
关键词:趋化因子      多发性硬化 
分类号:Q514.3 R744.5+1
出版年,卷(期):页码:2001,8(4):0-0
摘要:
炎性细胞被吸聚进入中枢神经系统(CNS)是包括多发性硬化(MS)在内的炎性脱髓鞘疾病的基本病理过程.通过实验性自身免疫性脑脊髓炎(EAE)研究表明,发生免疫介导的炎性反应时,被称为"趋化因子”的趋化性白细胞因子在调节淋巴细胞进入CNS组织的过程中发挥重要而独特的作用.
基金项目:
作者简介:
参考文献:
Fabry Z.Raine C.Hart M Nervous tissue as an immune compartment:the dialect of the immune response in the CNS 1994 Butcher E Leukocyte-endothelial cell re cognition:three steps to specificity and diversity 1991 Muller W.Weigl S.Deng X PECAM-1 is required for transendothelial migration of leukocy tes 1993 Tani M.Ransohff RM Do chemokines mediat e inflammatory cell invasion of the central nervous system parenchyma? 1994 Gerard C.Rollins BJ Chemokines and dise ase 2001(02) Baggiolini M Chemokines and leukocyte tr affic 1998 Huang D.Han Y.Rani MR Chemokines and Chemokine receptors in inflammation of nervous system:manifold roles and exquisite regulation 2000 Adams DH.Lioyd AR Chemokines:leukocyte recruitment and activation cytokine 1997 Murphy P The molecular biology of leukoc yte chemoattractant receptors 1994 Ransohoff RM.Hamilton TA.Tani M Astrocyte expression in murine experimental allergic encephalomyelitis 1993 Campbell JJ.Foxman EF.EC Butcher Chemoattractant recept or cross talk as a regulatory mechanism in leukocyte adhesion and migration 1997 Glabinski AR.VK Tuochy.RM Ransohoff Expression of chemokin es RANTES,MIP-1α,and GRO α correlates with inflammation in acute experimental autoimmune encephalomyelitis 1998(05) Ranshoff RM Chemokines in neurological diseases models:co rrelation between chemokine expression patterns and inflammatory pathology 1997 Hayashi M.Luo Y.Laning J Prod uction and function of monocyte chemoattractant protein-1 and other beta-chemo kines in murin glial cells 1995 Karpus WJ.Ransohoff RM Chemokine regulation of experiment al autoimmune encephalomyelitis:temporal and spatial expression patterns govern disease pathogenesis 1998 Miyagishi R.Kikuchi S.Fukazawa T Macrophage inflammatory protein-1α in the cerebrospinal fluid of patie nts with multiple sclerosis and other inflammatory neurological diseases 1995 Simpson K.J Newcombe.M Cuzner Expression of infla mmatory cells in multiple sclerosis lesions 1998(84) Franciotta D.Martino G.Zardini E Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatorry therapies 2001(1-2) Zhang GX.Baker CM.Kolson DL Ch emokines and chemokine receptors in the pathogenesis of multiple sclerosis 2000(01) Van Der Voorn P.Tekstra J.Beelen RH Expression of MCP-1 by reactive astrocytes in demyelinating multiple scle rosis lesions 1999(01)
服务与反馈:
文章下载】【加入收藏
中国神经免疫学和神经病学杂志 © 2009
编辑部地址:北京东单大华路1号   电话:010-58115071
传真:010-65242081   邮箱:zgsm@263.net